Potensi Ekstrak Daun Stevia (Stevia rebaudiana Bertoni) pada Formulasi Obat Kumur terhadap Aktivitas Antibakteri Streptococcus mutans

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Alifia Shuria Manikam Winda Shynta Pertiwi Arif Hidayanto Kun Harismah

Abstract

Stevia is a type of shrub plants are often used as a low calorie sweetening properties. In addition, stevia also has bioactive compounds such as steviosida, terpenoid and flavonoids to serve as antibacterial drugs. The mouthwash on the market generally contains chlorhexidine active ingredients which have side effects in long-term use. The purpose of this study was to evaluate the effectiveness and influence of concentration variation on stevia sting rinse formulation on Streptococcus mutans bacterial inhibition, pH value, species weight and organoleptis. The tested concentration variations are 10%, 15%, 20%, and 25%. This research method is an experimental laboratories research with Randomized Complete Random Research (RAL) design. From the research results obtained the highest bacterial inhibition is on the formulation of stevia mouthwash the highest concentration of 25% with a diameter of 4.15 mm inhibition. Followed concentration of 20% inhibitory diameter of 3.2967 mm, concentration of 15% inhibitory diameter of 2.6533mm, and at concentration of 10% inhibitory diameter of 2.5767mm. The value of bacterial inhibition diameter in stevia mouthwash occurs due to terpenoids and flavonoids as bioactive compounds, but also because of the main substance steviosida on stevia extract which has an enzyme that inhibits the work of fermentation of cariogenic bacteria.

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How to Cite
MANIKAM, Alifia Shuria et al. Potensi Ekstrak Daun Stevia (Stevia rebaudiana Bertoni) pada Formulasi Obat Kumur terhadap Aktivitas Antibakteri Streptococcus mutans. URECOL, [S.l.], p. 27-34, sep. 2017. Available at: <http://journal.ummgl.ac.id/index.php/urecol/article/view/1321>. Date accessed: 17 dec. 2017.
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